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Adjustment group for MS Airtraq AMIGOS ASTIC BEEP study BLISTER Study CALM Doxycycline in LAM ENOS e-Prescriptions Facial Pain fructose v glucose GI function # 1 GI function # 2 GOSIP HOVIS IBS-D IPS IR LEAP study LIMIT-1 LiSt # HipS MIBS MMHU Mood Disorder RCT n-3 PUFA Study Nerve blockade Orthodontics Reinforcement P3MC PATCH1 PATCH2 PCI study PEPS Pioglitazone v Placebo PITCH PPAR-gamma P-PROM Preventing miscarriage QSSMs SIMPLE SNAP SPIRA STAK Steriods for backpain STOP GAP The PONTI study The Rapor study The REFINE study TOMAS Vulval Dysfunction

Current trials The Nottingham CTU are currently supporting the following trials, by providing the listed services. For more information on the trials themselves please click on the 'read about this trial' link, in the table below. To see a list of trials the Nottingham CTU has supported in the past please click here. Evaluation adjustment group for people with MS Web-based randomisation Airtraq® versus standard laryngoscopes in unstable cervical spines. Web-based randomisation Acute Medicine Interface Geriatrician Outcome Study (AMIGOS) Web-based randomisation Autologous Stem Cell Transplantation for Crohn’s Disease (ASTIC) trial - trial website, trials summary Web-based randomisation Web-based data entry database Feasibility Study of Barrier Enhancement for Eczema Prevention - trial website Web-based randomisation A randomised controlled trial to compare the safety and effectiveness of doxycycline (200 mg/day) with prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid (BLISTER study) - trial website Web-based randomisation Web-based data entry database Psychological Treatments for Depression In Aphasic Stroke (CALM study) Web-based randomisation A randomised, double blind, placebo controlled trial of doxycycline in lymphangioleiomyomatosis. Web-based randomisation Web-based data entry database Efficacy of Nitric Oxide in Stroke trial (ENOS) - trial website Data monitoring committee statistical support Evaluation of the Electronic Prescription Service in Primary Care Web-based random timepoint selector Low dose Amitriptyline in the management of midfacial segment pain Web-based randomisation High fructose vs high glucose diet in overweight men Web-based randomisation Assessment of GI function to a large test meal by non-invasive imaging Web-based randomisation Assessment of GI function to a mixed meal by non-invasive imaging Web-based randomisation General or Spinal anaesthesia in Pelvic Surgery (GOSIP Trial) Web-based minimisation A Survey and feasibility RCT of pre discharge home visits for patients with a stroke (HOVIS) Web-based randomisation Ondansetron for the treatment of IBS-D Identifying the responder Web-based randomisation Web-based questionnaire database Individual Placement and Support for people with severe mental health problems: an implementation study of IPS with and without individual counselling as access routes to paid employment Web-based randomisation Investigating whether the magnitude of postoperative inflammatory and insulin resistant responses is related to body composition and physiological function of skeletal muscle & adipose tissue (IR trial) Web-based minimisation A pragmatic randomized controlled trial of physical activity as an aid to smoking cessation during pregnancy (LEAP study) Web-based randomisation Web-based data entry database Effect of topical imiquimod on lentigo maligna Trial management Web-based data entry database The use of LiDCO based fluid management in patients undergoing hip fracture surgery under spinal anaesthesia Web-based randomisation Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (MIBS). Web-based randomisation CRF data entry database Trial Management Statistics Trial supplies management system Evaluation of a Medical and Mental Health Unit compared with standard care for older people whose emergency admission to an acute general hospital is complicated by concurrent ‘confusion’ Web-based randomisation Randomised controlled trial of the clinical and cost effectiveness of a specialist mood disorders team for refractory unipolar depressive disorder Web-based randomisation The effect of n-3 PUFA supplementation in patients with steatosis due to non-alcoholic fatty liver disease Web-based randomisation Efficacy of continuous sciatic/posterior tibial nerve blockade via a neural sheath catheter in lower limb amputees Web-based randomisation Efficeiency and effectiveness of three methods of anchorage reinforcement in orthodontics Web-based randomisation A double blind parallel group randomised placebo controlled trial of Propranolol and Pizotifen in preventing migraine in children (P3MC) - trial website Web-based randomisation CRF data entry database Trial Management Statistics Prophylactic antibiotics for the prevention of recurrent leg cellulitis (PATCH1) - trial website Web-based randomisation CRF data entry database Prophylactic antibiotics for the prevention of recurrent leg cellulitis (PATCH2) - trial website Web-based randomisation CRF data entry database The addition of a goal-based motivational interview to standardised treatment as usual to reduce dropouts from a service for patients with personality disorder (PCI study) Web-based randomisation Psycho-education with problem solving (PEPS) therapy for adults with personality disorder: A community-based randomised controlled trial - trial website Web-based randomisation CRF data entry database Trial Management Statistics The effect of obesity-induced cytokine elevation on the molecular regulation of protein turnover and carbohydrate metabolism in human skeletal muscle Web-based randomisation Pilot study for a trial of ursodeoxycholic acid (UDCA) and/or early delivery for obstetric cholestasis (PITCH) Web-based randomisation Web-based data entry database PPAR-gamma therapeutic target for asthma Web-based data entry database Comparing immediate delivery with delay until signs of infection appear for preterm pre-labour rupture of the membranes (P-PROM) Web-based randomisation Web-based data entry database Preventing miscarriage using a Pessary Services pending confirmation Bacterial QSSMs, Innate and Adaptive Immunity in Healthy Subjects Web-based randomisation Low dose Aspirin as a prophylactic treatment for recurrent miscarriage (SIMPLE) - read about this trial Web-based randomisation Web-based data entry database Nicotine replacement therapy in pregnancy (SNAP) - read about this trial Web-based randomisation Web-based data entry database Data validation reports Trial monitoring reports Trial supplies management system Small particle inhaled steroids in refractory steroid-responsive asthma (SPIRA) Web-based randomisation Evaluating the implementation and effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity (STAK) Web-based paired cluster randomisation Effect of epidural steroid dose on low back disability scores Web-based randomisation A clinical trial to to investigate the best treatment for pyoderma gangrenosum. (The STOP GAP trial - trial website Web-based randomisation Prevention of Neural Tube defects by Inositol in conjunction with folic acid (The PONTI Study) Web-based randomisation A placebo controlled trial to evaluate Allopurinol in the prevention of tumour Recurrence in patients with superficial bladder cancer (The Rapor study) Web-based randomisation The REFINE study Web-based randomisation Web-based data entry database A multi-centre randomised controlled trial of rehabilitation aimed at improving outdoor mobility for people after stroke (TOMAS) Web-based randomisation CRF data entry database Trial Management Statistics Hypnotherapy to relieve coital pain due to vulval dysfunction Services pending confirmation

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